Cisplatin versus carboplatin
WebApr 10, 2024 · Triple-negative breast cancer (TNBC) is one of the most aggressive forms of breast cancer and constitutes 10–20% of all breast cancer cases. Even though platinum-based drugs such as cisplatin and carboplatin are effective in TNBC patients, their toxicity and development of cancer drug resistance often hamper their clinical use. Hence, novel … WebApr 16, 2024 · All four planned doses of cisplatin or carboplatin were received by 82.5% of the patients in the pembrolizumab-combination group and by 74.3% of those in the placebo-combination group; 76.5% and ...
Cisplatin versus carboplatin
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WebMay 14, 2024 · Ohe Y, Ohashi Y, Kubota K, et al: Randomized phase III study of cisplatin plus irinotecan versus carboplatin plus paclitaxel, cisplatin plus gemcitabine, and Vinorelbine plus Cisplatin for advanced non-small-cell lung cancer: Four-arm cooperative study in Japan. Ann Oncol 18: 317-323, 2007 Crossref, Medline, Google Scholar: 13. WebApr 4, 2024 · Carboplatin belongs to a class of medications known as platinum-containing compounds. It works by stopping or slowing the growth of cancer cells. Carboplatin is …
WebHotta K, Matsuo K. Long-standing debate on cisplatin- versus carboplatin-based chemotherapy in the treatment of advanced non-small cell lung cancer. J Thorac Oncol. 2007;2(1):96. 4. Hamdi T, Latta S, Jallad B, Kheir F, Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome. WebApr 19, 2024 · Adjusted HR (95% CI) of PFS for intraperitoneal (IP) carboplatin vs. intravenous (IV) carboplatin = 0.92 (0.75 – 1.13). Adjusted HR (95% CI) of PFS for IP cisplatin vs. IV carboplatin = 0.97 (0.79 – 1.19). There was no statistically significant difference in PFS between the IV regimen and either of the IP regimens in this subgroup …
WebJun 1, 2016 · Carboplatin ( cis -diammine-cyclobutanedicarboxylato-platinum (II)) was initially believed to have “comparable” therapeutic activity with cisplatin but is associated … WebJun 1, 2016 · In comparison with carboplatin, the use of cisplatin has been more extensively evaluated in the systemic management of endometrial cancer. A recent …
WebCisplatin carries a higher toxicity profile, including nausea, vomiting, neuropathy, renal insufficiency, and alopecia in comparison to carboplatin. When the goal of …
WebThere have been limited data comparing outcomes of carboplatin vs. cisplatin-based CRT, particularly in elderly. Material and methods: From the Surveillance, Epidemiology and End Results-Medicare registry, we identified 1878 patients >65 years of age with unresected stage III NSCLC that received concurrent CRT between 2002 and 2009. j.l. hufford coffee \\u0026 tea coWebMar 30, 2024 · The ubiquitin-proteasome system plays an important role in acquiring resistance to rituximab and chemotherapy agents in B-cell lymphoma. 9, 10 Carfilzomib (CFZ, PR-171) is a potent, tetrapeptide ketoepoxide–based inhibitor specific for the chymotrypsin-like active site of the 20S proteasome. It was first approved for the … j l hufford coffee \\u0026 tea company lafayetteWebJun 18, 2024 · Among chemotherapeutics with potentially lower nephrotoxicity, the inferiority of the carboplatin-Carboplatin, Etoposide, Bleomycin (CEB) versus BEP regimen has been previously demonstrated in randomized trials. [8,9] In the Horwich study, patients received either 4 series of BEP or 4 series of CEB. instation invilliaWebMar 30, 2024 · Rao S, Jones M, Bowman J, Tian C, Spano JP. POD1UM-303/InterAACT 2: A phase III, global, randomized, double-blind study of retifanlimab or placebo plus carboplatin-paclitaxel in patients with locally advanced or metastatic squamous cell anal carcinoma. Front Oncol. 2024 Aug 24;12:935383. doi: 10.3389/fonc.2024.935383. … instatin incWebApr 2, 2012 · Cisplatin is associated with more GI adverse effects, neurotoxicity, and renal function impairment, and its administration requires a prolonged hydration, 5, 6 but carboplatin is associated with more myelosuppression. Although the mechanisms of action are similar, it is unclear whether carboplatin and cisplatin have the same clinical efficacy. instation learning toolWebSelect search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources j l hufford coffee \u0026 tea company lafayetteWebOct 20, 2024 · Quality versus quantity of life in the treatment of patients with advanced small-cell lung cancer? a randomized phase III comparison of weekly carboplatin and … jlhv consulting ab