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Citrinin toxicity

WebSep 22, 2016 · Citrinin, but not ochratoxin A, toxicity is exacerbated in mutants with a defective antioxidant response or multidrug export. The indicated yeast strains were treated or not with 400 μM CIT (upper panel) or 400 μM OTA (lower panel) for the indicated time. Serial dilutions 1:1, 1:10, and 1:100 of the yeast cultures were then assayed for ... WebCitrinin is associated with poorly stored grains, but can be present in water-damaged buildings. It’s often found along with Ochratoxin, another kidney toxic mycotoxin. It has a very broad spectrum of negative impacts on …

Citrinin - an overview ScienceDirect Topics

WebCitrinin, a nephrotoxic mycotoxin, has been of growing importance also for the "International Agency for Research on Cancer", ever since its presumable role in the occurrence of Balcan endemic nephropathy (BEN) was discussed at the congress on "Mycotoxins, Endemic Nepthropathy and Urinary Tract Tumo … WebApr 30, 2024 · As common food and feed contaminants of fungal origin, the interest in the potential neurotoxicity of ochratoxin A, citrinin and their metabolites has recently increased. Primary porcine brain capillary endothelial cells were used to investigate cytotoxic or barrier-weakening effects of ochratoxin A, ochratoxin α, citrinin and dihydrocitrinone. hobbit edited version https://accweb.net

(PDF) Toxicological Properties of Citrinin - ResearchGate

Weband J zearalenols), nephrotoxic (ochratoxins, citrinin, oosporeine), dermonecrotic (trichothecenes), or immunosuppressive (aflatoxin B1, ochratoxin A, and T-2 toxin)…. Much of the published infor-mation on toxicity comes from studies in experimental animals, and these may not reflect the effects of mycotoxins on humans and other animals…. Web张大海职称：副教授办公电话：+86-532-6678-2215个人邮箱：[email protected]研究领域或方向：专业:天然产物化学、污染物生物降解、污水微生物处理、特殊功能材料改性分析特长:DNA提取与分离、分析深海热液出口微生物的提取、培养共生关系研究污水微生物处理谱图解析、化合物结构解析、天然产物 ... WebCitrinin appears to be toxic by multiple pathways including inhibition of nucleic acid synthesis, inhibition of microtubule assembly and tubulin polymerization, alteration of … hobbit eduelo

Red yeast rice - Mayo Clinic

Category:Citrinin and endosulfan induced maternal toxicity in pregnant …

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Citrinin toxicity

Toxicity of the mycotoxin citrinin and its metabolite …

WebCitrinin (CIT) and ochratoxin A (OTA) are mycotoxins produced by several species of the genera Aspergillus, Penicillium and Monascus. Both can be present as contaminants in … WebOchratoxins are produced by Aspergillus ochraceus and Penicil verrucosum, and citrinin is produced by Penicillium citrinum. These mycotoxins occur naturally in the environment and thereby commonly contaminate food/feed. Among ochratoxins, ochratoxin A (OTA) occurs with greatest frequency and is the most toxic. Citrinin cooccurs usually with OTA.

Citrinin toxicity

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WebThe role of altered mitochondrial function in citrinin-induced toxicity to rat renal proximal tubule suspensions*1 WebNational Center for Biotechnology Information

WebJan 1, 2024 · Description: Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess a broad spectrum of bioactivities, including antibacterial, antifungal, and potential anticancer and neuro … WebIt has caused billions of dollars in damage to crops and livestock. Common Aspergillus mycotoxins that are tested in the MycoTOX Profile include aflatoxin, ochratoxin, …

WebMay 22, 2014 · The enhanced toxicity of citrinin in a pdr5 mutant was further confirmed by an independent assay using FDA as a live cell stain upon acute citrinin stress in potassium phosphate buffer (Figure 4C). These results indicated that Pdr5 was a major citrinin export activity in yeast and we postulated that pdr5 mutant cells were more sensitive to the ... Web马博雅，张 佳，王雪莲，王昌禄（.天津科技大学 食品工程与生物技术学院，食品营养与安全教育部重点实验室，天津 300457；.廊坊出入境检验检疫局，河北 廊坊 065000）

WebApr 5, 2007 · Although citrinin is one of the well-characterized mycotoxins, information on its mechanism of toxic action is limited. Clinically, citrinin was shown to cause renal disease in poultry, pigs, dogs and rats [2, 3]. The electron transport system of the kidney and liver mitochondria were considered as the target of the toxic action of citrinin .

WebOct 13, 2024 · Immunoassays are developed based on antigen–antibody interactions. A mimotope is an effective recognition receptor used to study the mechanism of action of antigens and antibodies, and is used for improving the sensitivity of the antibody. In this study, we built a 3D structure of the citrinin (CIT) mimotope X27 and anti-CIT single … hr technology 2020WebMar 18, 2024 · The toxicity, higher than additive toxicity, was induced by citrinin and patulin when combined with ochratoxin A or ochratoxin B in Lilly Laboratories cell porcine kidney 1 (LLC-PK1) cells . As, Cd and Pb induced synergistic action in … hr technology 2021 by josh bersinWebThe role of altered mitochondrial function in citrinin-induced toxicity to rat renal proximal tubule suspensions*1 hr technology conference \\u0026 expoWebCitrinin is a mycotoxin which is often found in food. It is a secondary metabolite produced by fungi that contaminates long-stored food and it causes different toxic effects, like … hobbit edits redditWebApr 11, 2024 · Damage to the reproductive system is the key factor leading to male infertility. Citrinin (CTN) is produced by Penicillium and Aspergillus in nature, and is definitely found in food and animal feed. Studies have revealed that CTN can cause damage to male reproductive organs and reduce fertility, but the mechanism of toxicity has not been … hrtechprivacy.comWebApr 6, 2016 · Regarding its relative toxicity, citrinin appears to be considerably less toxic to poultry than oosporein or ochratoxin A, two other important nephrotoxic mycotoxins. High levels of citrinin may affect the … hobbit editionsWebThis study aimed toevaluate the toxic, cytotoxic, mutagenic and oxidant/antioxidant activities of acetonitrile extract (AEPc), citrinin (CIT) and dicitrinin-A (DIC-A) of Penicillium citrinum. For this, the test substances at 0.5; 1.0; 1.5 and 2 μg/mLwere exposed for 24 and 48 h in Artemia salina , and 48 h in Allium cepa test systems. hobbit editing