2024 Kashin beck disease gwas

Kashin beck disease gwas

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August undefined, 2024

WebbDuring the past several decades, etiological and geochemical studies tend to link the Kaschin-Beck Disease (KBD) to the deficiency of some specific trace elements (e.g., selenium and iodine) in the environment; however the link has been proven inconclusive. In this work, we have investigated the rel … Webb15 jan. 2016 · Objectives: To identify the differences and similarities of differentially expressed genes in peripheral blood mononuclear cells (PBMCs) between Kashin–Beck disease (KBD) grades I and II.Method: In total, 100 patients with KBD and 100 healthy controls were selected from a KBD endemic area and divided into 100 pairs of KBD vs. …

Field synopsis and meta-analyses of genetic epidemiological …

WebbKashin beck’s disease Introduction Kashin-Beck disease (KBD) is an endemic chronic osteo-chondropathy, which is prevalent at the Eastern Siberia of Russia, North Korea, … WebbKashin–Beck disease ( KBD) is a chronic, endemic type of osteochondropathy (disease of the bone) that is mainly distributed from northeastern to southwestern China, including 15 provinces. [1] As of … elementary school demographic profile

Integrative Analysis of Genome-Wide Association Studies and …

WebbDisabling osteochondrodysplasia with osteosclerosis, cone-shaped metaphysis, and shortening of the diaphysis. It is endemic in parts of Siberia and northern China. … Webb× Close. The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. Webb6 apr. 2024 · The mission of the Public Health Genomics is to integrate advances in human genetics into public health research, policy, and programs football pregame hype chants

Genetic variants in the ITPR2 gene are associated with Kashin‐Beck ...

WebbKashin-Beck disease (KBD) is a chronic osteo- chondropathy, which is mainly characterized by cartilage degeneration, cartilage matrix degradation, chondrocyte necrosis, and apoptosis. KBD usually involves children ages3–12years,andthepatientsexperienceseriousjoint pain, joint deformities, and … WebbKashin-Beck Disease. KBD symptoms such as morning stiffness in the joint and joint pain are comparable with the symptoms of FMS (Allander, 1994; Rayman, 2000). From: … football pregame music playlistWebb21 feb. 2024 · In Proceedings of the international workshop on kashin-beck disease and non-communicable diseases Vol. 74 96–101 (World Health Organization, Geneva, 1990). elementary school custodian job description

"Webb7 maj 2024 · Abstract Background Kashin‐Beck Disease (KBD) is a chronic, endemic osteoarthropathy. Inositol 1,4,5‐triphosphate receptor type 2 ... In an independent GWAS, Wu et al. identified two common variants rs718314 and rs1049380 in ITPR2 gene as novel susceptibility loci for renal cell carcinoma (RCC; Wu et al., 2012). " - Kashin beck disease gwas

Kashin beck disease gwas

Pathway-based network analyses and candidate genes …

Webb3 maj 2024 · Kashin-Beck Disease (KBD) is a type of endemic, chronic, and disabling osteoarthropathy with high disability. KBD is also named as endemic … Webb20 aug. 2015 · Kashin-Beck Disease (KBD) is a chronic disabling osteochondropathy (Stone 2009). The primary clinical manifestations of KBD include pain, limited motion, …

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Kashin–Beck disease (KBD) is a chronic, endemic type of osteochondropathy (disease of the bone) that is mainly distributed from northeastern to southwestern China, including 15 provinces. As of 2011, Tibet has the highest incidence rate of KBD in China. Southeast Siberia and North Korea are other affected areas. KBD usually involves children ages 5–15. To date, more than a million individuals have had KBD. The symptoms of KBD include joint pain, morning stiffness in the join… WebbAnother independent sample of 1717 subjects was genotyped for a genome-wide association study (GWAS) using Affymetrix Human SNP 6.0 Arrays. Single …

Webb1 maj 2024 · Kashin-Beck Disease (KBD) is a type of endemic, chronic, and disabling osteoarthropathy with high disability. ... (GWAS) at a genome-wide significance level, the comprehensive and positive genes were obtained from the supplementary data of … Webb13 okt. 2015 · GWAS meta-analysis identified six candidate genes with pleiotropic effects, including PDGFD, SOX5, DPYD, CTR9, SPP1, and COL4A1. GO analysis identified 16 significant GO shared by KBD and the...

Webb9 okt. 2014 · Kashin‐Beck disease (KBD) is a chronic osteochondropathy, which is mainly characterized by cartilage degeneration, cartilage matrix degradation, chondrocyte … WebbSelenium deficiency causes Keshan disease (cardiomyopathy) and Kashin-Beck disease (osteoarthritis) and has been linked to oxidative stress, inflammation, ... we conducted a two-stage genome-wide association study (GWAS) by using the data from two cohorts to examine the effects of genetic variation on serum selenium concentrations. 2. Subjects ...

Webb7 maj 2024 · Kashin‐Beck Disease (KBD) is a chronic, endemic osteoarthropathy, which manifests as joint deformities and growth retardation ... In an independent GWAS, Wu et al. identified two common variants rs718314 and rs1049380 in ITPR2 gene as novel susceptibility loci for renal cell carcinoma (RCC; Wu et al., 2012).

Webb23 apr. 2016 · Kashin-Beck disease (KBD) is an endemic osteochondropathy (Stone 2009 ), characterized by cartilage degeneration, cartilage matrix degradation, … elementary school dean of studentsWebbKashin-Beck disease (KBD) top three specific PPI networks. A: From genes detected by genome-wide association studies (GWAS); B: From genes detected by microarray analysis; C: From genes detected by exome sequencing; the red nodes mean genes in the KBD-related gene list, the green nodes are genes not in the KBD-related gene list. elementary school crossword puzzlesWebb1 nov. 2011 · To evaluate the performance of SWGDT, a real GWAS dataset of Kashin-Beck disease (KBD) was analyzed. Immunohistochemisty was also performed to validate the relevance of identified gene with KBD. football pregame devotionsWebb15 dec. 2014 · Kashin–Beck disease (KBD) is a serious osteoarthropathia, mainly characterized by excessive chondrocyte necrosis and apoptosis. The molecular … football pre game warm up drillsWebb9 okt. 2014 · Kashin-Beck disease (KBD) is a chronic osteochondropathy, the pathogenesis of which remains elusive. The aim of this study was to identify susceptibility genes for KBD by conducting a 2-stage genome-wide association study (GWAS). Methods elementary school desk organizersWebb15 dec. 2014 · Kashin-Beck disease (KBD) is a serious osteoarthropathia, mainly characterized by excessive chondrocyte necrosis and apoptosis. The molecular … football premier league prize moneyWebb9 juli 2012 · Kashin–Beck disease (KBD) is characterized by chondrocytic necrosis and apoptosis, cartilage degeneration and matrix degradation ... miRNA–mRNA target databases, GWAS databases, KEGG and so on. IPA is easy to operate and offers high-quality diagrams of pathways and networks that contain much information using a visual … elementary school desk organization tips