WebKrüppel-like factor 5 (KLF5) is a member of the KLF family. Recent studies have suggested that KLF5 regulates the expression of a large number of new target genes and … WebJun 11, 2024 · Members of the Krüppel-like factor (KLF) family of transcription factors, which are characterized by the presence of three conserved Cys2/His2 zinc-fingers in their C-terminal domains, control a wide variety of biological processes. In particular, recent studies have revealed that KLFs play diverse and essential roles in the control of metabolism at …
KLF4 - an overview ScienceDirect Topics
WebDesigning specific targets in regulating the expression of KLF is a potential therapy. Abstract. Kruppel-like factors (KLFs) are a family of zinc finger transcription factors that have been found to play an essential role in the development of various human tissues, including epithelial, teeth, and nerves. In addition to regulating normal ... WebFeb 1, 2024 · KLF proteins are critical regulators of physiological systems including cardiovascular, hematological, respiratory, digestive, and immune system. They are involved in disorders like cardiovascular disease, cancer, obesity and inflammatory diseases. officer down in california
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WebKlf knockout mice, such as Klf1, Klf2, KLF3, Klf6, and Klf13 [1-6] demonstrating the significant role of Klfs in hematopoiesis. The role of Klf members in leukocyte development and hematopoiesis-associated diseases has also been reported [7]. Moreover, due to similarities in their structures and functions, cross-regulation of Klf members was WebNational Center for Biotechnology Information WebThe KLF file extension indicates to your device which app can open the file. However, different programs may use the KLF file type for different types of data. While we do not … my dear sponsor