Mob kinase activator 1a
WebPharos : Target Details - MOB1A Jump to section: close Descriptive Data Protein Summary Protein Classes IDG Development Level Summary Expression Data Protein Sequence and Structure Related Tools Behavioral Data Approved Drugs Active Ligands Protein-Protein Interactions Nearest Tclin Targets Pathways Predicted Viral Interactions Phenotypic Data Web21 jan. 2024 · LATS1 and LATS2, together with the regulatory proteins MOB kinase activators 1A (MOB1A) and MOB1B, phosphorylate yes-associated protein 1 (YAP; homologue to the Drosophila protein Yorkie...
Mob kinase activator 1a
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Web14 nov. 2024 · Abstract The Hippo pathway plays a crucial role in cell proliferation and apoptosis and can regulate stem cell maintenance and embryonic development. MOB kinase activators 1A and 1B (Mob1a/b) are key components of the Hippo pathway, whose homozygous deletion in mice causes early embryonic lethality at the preimplantation stage. Web21 mrt. 2024 · MOB1A (MOB Kinase Activator 1A) is a Protein Coding gene. Diseases associated with MOB1A include Sveinsson Chorioretinal Atrophy and Neurofibromatosis, Type Ii . Among its related pathways are Wnt / Hedgehog / Notch and PI3K / Akt Signaling . An important paralog of this gene is MOB1B.
WebMOB kinase activator 1B Protein also known as : Mps one binder kinase activator-like 1A . Gene name : MOB1B; Family name : MOB1/phocein Protein Recommended name MOB kinase activator 1B Alternative names Web10 jan. 2024 · Complete information for MOB1AP1 gene (Pseudogene), MOB Kinase Activator 1A Pseudogene 1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium
WebNCBI Full Gene Name MOB kinase activator 1A; NCBI Gene Aliases 4022402H07Rik, MOB1, MOB4B, Mobk1, Mobk1b, Mobkl, Mobkl1b; Primer Type Gene-specific Primers; Add to Compare List. OriGene Technologies. 9620 Medical Center Drive # 200 Rockville, Maryland 20850. United States WebMOB kinase activator 1A Synonyms 4022402H07Rik, MGC:6884, Mobk1b, Mobkl1b Feature Type protein coding gene IDs MGI:2442631 NCBI Gene: 232157 Alliance gene page Transcription Start Sites 4 TSS Location & Maps more Sequence Map Chr6:83303016-83319794 bp, + strand From NCBI annotation of GRCm39 Genetic Map …
WebPredicted to enable protein kinase activator activity. Predicted to be involved in hippo signaling and positive regulation of protein phosphorylation. Predicted to be located in cytosol; nucleolus; and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human MOB1A (MOB kinase activator 1A).
Web23 jan. 2007 · The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. trackwell vms loginWeb1 mrt. 2001 · MOB kinase activator-like 1A Gene MOB1A Status UniProtKB reviewed (Swiss-Prot) Organism Arabidopsis thaliana (Mouse-ear cress) Amino acids 215 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History Add a publication Function trackwest companies houseWeb(RefSeq) MOB kinase activator 1A isoform X1. KO: K06685 : MOB kinase activator 1: Organism: phas Phyllostomus hastatus (greater spear-nosed bat) Pathway: phas04390 : Hippo signaling pathway: phas04392 : Hippo signaling pathway - multiple species: Brite: KEGG Orthology (KO) [BR:phas00001] trackwest dog clubhttp://antibodysystem.com/index/pdf?id=12144 the room 2 plazaWeb8 dec. 2024 · Mob1b MOB kinase activator 1B [ (Norway rat)] Gene ID: 360920, updated on 8-Dec-2024 Summary Predicted to enable kinase binding activity and protein kinase activator activity. Predicted to be involved in hippo signaling; positive regulation of protein phosphorylation; and regulation of protein autophosphorylation. the room 2 pcWebHomology of these components in mammals is Ste20-like kinase 1/2 (MST1/2), large tumor suppressor 1/2 (LATS1/2), Salvador 1 protein (SAV1, also called WW45), MOB kinase activators 1A and 1B (MOB1A/B) and Yes-associated protein/transcriptional coactivator with PDZ-binding motif (YAP/TAZ), respectively. trackwell repair lincoln neWebLegK7MOB kinase activator 1ADI(HYDROXYETHYL)ETHERHEXAETHYLENE GLYCOLPHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERTETRAETHYLENE GLYCOLZINC ION NCBI National Center forBiotechnology Information Search 6MCP: L. pneumophila effector kinase LegK7 (AMP-PNP bound) in complex with human MOB1A … the room2pc下载